ea0034p365 | Steroids | SFEBES2014
Powlson Andrew S
, Koulouri Olympia
, Challis Benjamin G
, Cheow H K
, Buscombe John
, Koo Brendan
, Brown Morris J
, Gurnell Mark
Although adrenal vein sampling (AVS) remains the gold-standard for distinguishing unilateral and bilateral disease in primary hyperaldosteronism (PHA), it is technically demanding and not always feasible. Metomidate (MTO), a potent inhibitor of CYP11B1 and CYP11B2, can be C11H3-labelled as a PET tracer (11C-MTO), and we have previously shown it to be an alternative to AVS for localising unilateral aldosterone-producing adenomas (APAs) (Burton <...